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KMID : 0370220230670050318
Yakhak Hoeji
2023 Volume.67 No. 5 p.318 ~ p.323
Five-year Trends in Drug Advertisement Review by the Anatomical and Therapeutic Classification of Pharmaceutical Products and Factor Analysis for Improvement of Quality of Advertisement
Cho Woo-Yeon

Jeon Ha-Lim
Abstract
There has been no study investigating which drug advertisements have recently increased or what decisions theDrug Advertisement Review Committee made based on the therapeutic classification of the drug. This study aimed toexamine the status and trend of drug advertisement review by the Anatomical Therapeutic Chemical (ATC) Classificationover the 5 years and identify factors that may increase the likelihood of receiving a decision other than ¡®accepted¡¯. Weobtained drug advertise review data from the Korea Pharmaceutical and Bio-Pharma Manufacturers Association (2017-2021). The number of reviewed drugs and 5-year increase rate were calculated by ATC classification. We performed alogistic regression to compute odds ratios (ORs) for potential contributing factors. From 2017 to 2021, the overall reviewed drugs increased by 84.3%. The 5-year increase rate for ¡®modification-needed¡¯ (236.3%) and ¡®inadequate¡¯ (312.8%)decisions was higher than the overall 5-year increase rate. Drugs related to the Alimentary Tract and Metabolismunderwent more advertisement reviews than those from other categories. Nearly all categories demonstrated an increasingtrend in online media. Online media [OR=1.34; 95% confidence interval (CI), 1.27-1.42], drugs for Musculo-skeletalsystem (OR=1.13, 95% CI, 1.01-1.22) and sensory organs(OR, 1.82; 95% CI=1.58-2.08) were significantly increase theprobability of receiving a decision other than ¡®accepted¡¯. Our results will be useful to improve drug advertisement reviewsystem and promote self-censorship of pharmaceutical companies.
KEYWORD
Drug advertisement review, Anatomical Therapeutic Chemical Classification, Trend analysis, Factor analysis
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